As a U.S. Deputy Marshal based in Miami, Florida's Gold Coast, Karen Sisco must deal with the underbelly of South Beach nightlife and Palm Beach high life while tracking down fugitives. She also struggles to win the respect of her fellow officers. Karen occasionally gets advice from her father, a retired Miami police officer turned private investigator, who is Karen's confidant, counselor, and confessor.
E1
An effort to apprehend a fugitive goes wrong, almost putting a bullet through Karen's heart and leaving one man dead. But she's having trouble remembering what happened so she can write a report to satisfy Internal Affairs. Meanwhile, Karen's in for heartache of a different kind when she learns that the good natured charter fisherman she's dating may actually be a bank robber, at least according to the FBI agents on his trail.
E2
With only six months to go on their prison term, the not too bright Salchek brothers are duped into escaping from jail, and stealing a baseball worth millions from mob boss Charlie Lucre. Then they'll finally be able to buy a double wide trailer for their loving mother. Having caught them once before, Karen must race against Lucre, his hit men, and an overzealous FBI agent to find them and put them back behind bars.
E3
A smooth talking con man catches a lucky break, allowing him to escape right under Karen's nose. Determined to bring him back, Karen must first contend with an old FBI adversary, a former FBI boyfriend (who's still married), and an ex-mob accountant inexplicably out of hiding from the Witness Protection Program.
E4
A reluctant Karen partners with Konner, a US Marshal who goes by his own rules, to find three parolees on the run. But Karen is unaware that the ex-cons are running from Konner--who plans to mete out his own deadly brand of justice.
E5
Karen must protect an annoying counterfeiter who says he remembers her from high school (she doesn't remember him at all). Meanwhile, a robber picks up right where he left off hours after being released from prison.
E6
Karen's fling with a Florida Marlins pitcher takes a backseat to a real star-crossed romance when she pursues a prisoner, who keeps escaping to see his one true love, a stripper longing for a new life. Complications ensue when his best friend gets her involved with the Russian mob.
E7
Karen gets a second chance to bring in a fugitive accountant on the lam for murder and grand theft while Marshall takes on an attractive new client who wants her husband investigated for adultery.
E8
A routine trip to the bank goes horribly wrong for Karen and Marshall when they are held hostage at gunpoint after a botched holdup. The FBI agent on the scene is a little too eager to storm the bank, which might jeopardize the lives of the hostages.
E9
Karen takes temporary custody of a smart-aleck murder witness, a wily preteen girl whose incarcerated father seeks an early parole to dodge a death threat and collect a stash of stolen money.
E10
Karen goes undercover to investigate the overdose related death of her father's pal, a down on his luck ex-con Marshall suspects was murdered because of his gambling debts.